Self-disseminating vaccines for emerging infectious diseases
نویسندگان
چکیده
منابع مشابه
Self-disseminating vaccines for emerging infectious diseases
Modern human activity fueled by economic development is profoundly altering our relationship with microorganisms. This altered interaction with microbes is believed to be the major driving force behind the increased rate of emerging infectious diseases from animals. The spate of recent infectious disease outbreaks, including Ebola virus disease and Middle East respiratory syndrome, emphasize th...
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The complex interaction between a microbial pathogen and a host is the underlying basis of infectious disease. By understanding the molecular details of this interaction, we can identify virulence-associated microbial genes and hostdefense strategies and characterize the cues to which they respond and mechanisms by which they are regulated. This information will guide the design of a new genera...
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Disease caused by Shiga toxin-producing Escherichia coli (STEC) ranges from self-limiting diarrhea to hemorrhagic colitis and hemolytic uremic syndrome (HUS). Serotype O157:H7, the most frequently implicated STEC causing hemorrhagic colitis and HUS, has been isolated from large foodborne outbreaks, as well as sporadic cases, in North America and abroad. However, 60 STEC serotypes have been impl...
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ژورنال
عنوان ژورنال: Expert Review of Vaccines
سال: 2015
ISSN: 1476-0584,1744-8395
DOI: 10.1586/14760584.2016.1106942